Canada pharmacy orlistat

You can buy Orlistat (Xenical/Alli) as an over-the-counter alternative to Wegovy in the UK.

However, Orlistat is a very different type of weight-loss medication, and research suggests it’s not as effective as Wegovy in supporting weight loss.

What’s the difference between Orlistat and Wegovy?

Wegovy and Orlistat are weight-loss medications approved for use in the UK. However, they are different medications with distinct dosing schedules, costs, and mechanisms of action on the body.

Orlistat is a lipase inhibitor. Lipases are gut enzymes that break down fat from food, enabling the gut to transport fat into the body to be burnt for energy or stored in our fat cells for later use.

Orlistat blocks lipases, preventing some of the dietary fat from our meals from being digested. This leads to fewer calories being absorbed, which can support weight loss.

Orlistat is a prescription medication produced by two pharmaceutical companies in the UK:

  • GlaxoSmithKline: Alli, 60 mg and available over the counter (no prescription)
  • Roche: Xenical, 120 mg and available with a prescription

Wegovy is a weight-loss jab manufactured by Novo Nordisk. It’s a weekly weight-loss injection with semaglutide as the active ingredient.

Semaglutide is a that helps reduce hunger and appetite, allowing you to eat fewer calories, lose weight, and manage your blood sugar levels.

Wegovy is approved in the UK for individuals living with obesity to help them eat fewer calories and lose weight.

How much do Wegovy and Orlistat cost?

The over-the-counter version of Orlistat will cost around £18 a month, so it’s a very affordable medication.

In comparison, buying Wegovy and the injectable pens required for four weeks from Second Nature will cost £229 a month, rising to £299.

Should I try Orlistat or Wegovy for weight loss?

Orlistat is an affordable medication that is generally well-tolerated. However, it’s less effective than Wegovy. Wegovy is twice as effective as Orlistat for weight loss after one year.

So, if you’re looking for the most affordable weight-loss pill you can purchase over the counter, then Orlistat could be an option.

However, if you have a higher budget and are looking for the most effective weight-loss injection in the UK, semaglutide is a better choice.

Wegovy’s not a magic pill

Semaglutide is designed as an additional tool for weight management and, in most cases, shouldn’t be considered a lifelong medication.

Instead, it should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.

Ideally, we’d be able to lose weight without medication and lifestyle changes would be enough to support weight loss in the long term.

We’d generally recommend trying Second Nature’s before considering a weight-loss jab.

Changing your habits is the most sustainable way to achieve long-term weight loss, and it’s also less expensive.

At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.

In 2022, the NHS in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.

Second Nature was more than twice as effective at supporting weight loss than the other four providers.

However, if you’ve decided to try semaglutide (when it’s available) but need support in making positive changes to your lifestyle, Second Nature could be an option for you. But it’s worth noting that we have strict eligibility criteria.

Second Nature has (among the most extensive medication supply chain in the UK)

than any of our providers

Second Nature is the only pharmacy in the UK that is not linked to the medication you’re receiving.

Salt Composition in both

Salt Composition

Orlistat 120mg(same for both)

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Frequently Asked Questions

How long does it take for the capsules to work and take effect?1-itchie Capsules – start working fast after taking the capsules.

Always check the ingredients

The active substance is 120 mg of Orlistat 120mgEach capsule contains:1g of Orlistat 120mg1 capsule contains:

Important Information

You may only buy Xenical 120mg Capsules by express prescription from your doctor. However, we always ensure that your medicine is of the best quality and require special handling for your particular needs. Therefore, if you have any questions or concerns about the quality of your medicines or about your health, please speak to your doctor. Your satisfaction is our top priority. Your information will never be shared. Xenical 120mg Capsules are addictive and your health and safety are our utmost priorities.

You can buy Orlistat (Xenical/Alli) as an over-the-counter alternative to Wegovy in the UK.

However, Orlistat is a very different type of weight-loss medication, and research suggests it’s not as effective as Wegovy in supporting weight loss.

What’s the difference between Orlistat and Wegovy?

Wegovy and Orlistat are weight-loss medications approved for use in the UK. However, they are different medications with distinct dosing schedules, costs, and mechanisms of action on the body.

Orlistat is a lipase inhibitor. Lipases are gut enzymes that break down fat from food, enabling the gut to transport fat into the body to be burnt for energy or stored in our fat cells for later use.

Orlistat blocks lipases, preventing some of the dietary fat from our meals from being digested. This leads to fewer calories being absorbed, which can support weight loss.

Orlistat is a prescription medication produced by two pharmaceutical companies in the UK:

  • GlaxoSmithKline: Alli, 60 mg and available over the counter (no prescription)
  • Roche: Xenical, 120 mg and available with a prescription

Wegovy is a weight-loss jab manufactured by Novo Nordisk. It’s a weekly weight-loss injection with semaglutide as the active ingredient.

Semaglutide is a that helps reduce hunger and appetite, allowing you to eat fewer calories, lose weight, and manage your blood sugar levels.

Wegovy is approved in the UK for individuals living with obesity to help them eat fewer calories and lose weight.

How much do Wegovy and Orlistat cost?

The over-the-counter version of Orlistat will cost around £18 a month, so it’s a very affordable medication.

In comparison, buying Wegovy and the injectable pens required for four weeks from Second Nature will cost £229 a month, rising to £299.

Should I try Orlistat or Wegovy for weight loss?

Orlistat is an affordable medication that is generally well-tolerated. However, it’s less effective than Wegovy. Wegovy is twice as effective as Orlistat for weight loss after one year.

So, if you’re looking for the most affordable weight-loss pill you can purchase over the counter, then Orlistat could be an option.

However, if you have a higher budget and are looking for the most effective weight-loss injection in the UK, semaglutide is a better choice.

Wegovy’s not a magic pill

Semaglutide is designed as an additional tool for weight management and, in most cases, shouldn’t be considered a lifelong medication.

Instead, it should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.

Ideally, we’d be able to lose weight without medication and lifestyle changes would be enough to support weight loss in the long term.

We’d generally recommend trying Second Nature’s before considering a weight-loss jab.

Changing your habits is the most sustainable way to achieve long-term weight loss, and it’s also less expensive.

At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.

In 2022, the NHS in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.

Second Nature was more than twice as effective at supporting weight loss than the other four providers.

However, if you’ve decided to try semaglutide (when it’s available) but need support in making positive changes to your lifestyle, Second Nature could be an option for you. But it’s worth noting that we have strict eligibility criteria.

Second Nature has a team-based pricing programme | Read more: Wegovy offers SingleCare as a once-a-day price for weight-loss medications, and Second Nature has a range of medication available for multiple sclerosis and other causes.

The cost of generic Orlistat can vary from £4- £12 per month. Speak to your doctor or pharmacist for assistance determining the appropriate dosage and treatment plan.

Generic Orlistat is available at lower cost than branded Orlistat. Brand name generic Orlistat is available at a lower cost than branded generic Orlistat. Generic Orlistat cost less than branded generic Orlistat and is ideal for patients who need a lower cost alternative to Orlistat.

Generic Orlistat is available in lower cost under the brand names Alli and Alli XR. Generic Orlistat is available in a lower cost strength (up to £12 per month).

Orlistat Prices

As with all prescription medication, you should expect to pay the high costs associated with medication. The correct pricing can vary significantly depending on the dosage you have been prescribed and the pharmacy you visit. To ensure you’re getting the best value for your money, it’s best to compare prices online from the comfort of your own home. This is a good idea since prices can vary at pharmacy platforms and retailers.

Generic Orlistat pricesare lower than other pharmacies but generally are higher. While not as high as the competitors, they do have a limited selection of medications and are more affordable compared to the other pharmacies in your area. In addition, they offer a free consultation service and can save you as much as £9.99 per consultation.

Often referred to as the “Generic Drugstore,” the prices quoted above are general prescription medication prices. This can be as low as £3- £6 per month but can be as high as £12 for a 30-day supply of Orlistat.

These are generally lower cost alternatives to Orlistat and are intended for lower-income patients. They should be considered for patients who require a lower cost alternative to Orlistat.

Patients with a valid prescription for Orlistat can obtain this medication through a regulated pharmacy. If you have any questions about the cost of this medication, ask your doctor or pharmacist.

References:

  1. Alli (Orlistat). Prescription information for Alli, Alli XR, and Xenical. Prescription information for Alli, Alli XR, and Xenical Prescription Drug Information.. Updated May 5, 2025. Available from. Accessed July 19, 2025.
  2. Alli (Alli XR). Prescription information for Alli, Alli XR, and Xenical..
  3. Orlistat (generic Xenical).
Online Prescription Services

For the best price, visit Alli.

FeatureAlli (Orlistat)Alli XR (Orlistat)
Feature 1Low prices, quick shipping, discreet packaging.
Feature 2High prices, quick, convenient.
Feature 3Discreet, secure ordering.
Feature 4Discreet, low prices, fast delivery.
Generic AvailabilityYes
Online Prescription Services.Is this service available to help patients afford their prescription medication?